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Street Address
496 Zhongshan Road
Country/Region
China (Mainland)/Hubei
Telephone

86-027-88215853

Naphazoline hydrochloride
Naphazoline hydrochloride
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0 per 0
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Negotiable
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Quick Details
Place of Origin:
China (Mainland)
Brand Name:
Pharmlab
Model Number:
550-99-2
Packaging & Delivery
Disguised package; Foil bag
Product Description


Pharmaceutical Intermediates Naphazoline Hydrochloride for Antihistamine / Whatsapp:+8615308670259


Basic Info.


Product Name:Naphazoline hydrochloride

Appearance: White to off-white crystaline powder

Synonyms:naphconforte;naphthasoliumchloride;niazol;privinehydrochloride;prizolehydrochloride;rhinantin;rhinoperd;sanorin-spofa

CAS:550-99-2

MF:C14H15ClN2

MW:246.74

EINECS:208-989-2

mp:254-260

Boiling point: 440.5° C at 760 mmHg

Flashing point: 220.2° C °C

Water Solubility:170 g/L (20 ºC)

Usage:adrenergic blocker,antihistamine



Descriptions

 

Naphazoline hydrochloride is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops.



Applications

 

Naphazoline is a decongestant used to relieve redness, puffiness, and itchy/watering eyes due to colds, allergies, or eye irritations (smog, swimming, or wearing contact lenses). It is known as a sympathomimetic (alpha receptor agonist) that works in the eye to decrease congestion.

Some brands of naphazoline eye drops also contain other ingredients. Lubricants (such as glycerin, hypromellose, or polyethylene glycol 300) help protect the eyes from more irritation. Zinc sulfate, an astringent, helps reduce redness and irritation.



Warnings and contraindications

 

A few warnings and contraindications that apply to all naphazoline-containing substances intended for medicinal use are:

 


Hypersensitivity to naphazoline


Patients taking MAO inhibitors can experience a severe hypertensive crisis if given a sympathomimetic drug such as naphazoline HCl

Use in infants and children can result in central nervous system depression, leading to coma and marked reduction in body temperature

Should be used with caution in patients with severe cardiovascular disease including cardiac arrhythmia and in patients with diabetes, especially those with a tendency toward diabetic ketoacidosis

Drug interactions can occur with anaesthetics that sensitize the myocardium to sympathomimetics (e.g. cyclopropane or halothane cautiously)

Exercise caution when applying prior to use of phenylephrine.

Extended use may cause rhinitis medicamentosa, a condition of rebound nasal congestion.

A possible association with stroke has been suggested.



How to use naphazoline ophthalmic


Follow all directions on the product package, or use as directed by your doctor. If you are uncertain about any of the information, consult your doctor or pharmacist.

 

To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.

 

Remove contact lenses before applying the eye drops. Wait at least 10 minutes after using this medication before inserting contact lenses.

 

Before using, check this product visually. Do not use if the liquid has changed color or is cloudy. Use in affected eye(s) as directed.

 

Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over the eye and place 1 drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of the eye near the nose and apply gentle pressure. This will prevent the medication from draining away from the eye. Try not to blink and do not rub the eye. Repeat these steps if your dose is for more than 1 drop and for the other eye if so directed.

 

Do not rinse the dropper. Replace the dropper cap tightly after each use.

 

If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.

Overuse of this type of medication may result in increased eye redness (rebound hyperemia). Tell your doctor if this occurs or if your condition persists or worsens after 48 hours. If you develop eye pain/vision changes or think you may have a serious medical problem, seek immediate medical attention


Delivery Process :

 

1. Describing items , quantities , and the destination country , and Confirming all details ,  placing order .


2.Confirm the quotation , we send and transportation recommended .


3.Informing us the detailed contact information , including contact person/company, address, mobile number, ZIP code and special requirements .


4. Packing pictures and tacking code are provided within 24 hours after receiving the payment . Updated tracking information will be provided every other day .


5. After-sale service : Any questions or problems after receiving the product , please feel free to contact us . Problems would be solved immediately .


Any needs, please feel free to contact me.


Whatsapp:+8615308670259

Skype:+8615308670259


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