CAS 112529-15-4 Pharmaceutical Bulking Cycle Steroids Pioglitazone Hydrochloride for Diabetes Treatment / Whatsapp:+8615308670259
Product Name: Pioglitazone HCl
Appearance: White Crystalline Powder
Suitable for: Adult
CAS No.: 112529-15-4
Molecular Weight: 392.9
Molecular Formula: C19h21cln2o3s
Transport Package: Disguised Packing for Delivery Guarantee!
Certification: GMP, ISO 9001, USP, BP
Specification: Pharmaceutical Grade
HS Code: 2937390000
Pioglitazone Hydrochloride is the hydrochloride salt preparation of Pioglitazone, a specific ligand of PPAR-γ (peroxisome proliferator-activated receptor-γ). Pioglitaze is a thiazolidinedione compound described to produce antiinflammatory and antiarteriosclerotic effects.
Pioglitazone is demonstrated to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress increased TNF-α mRNA produced by aspirin-induced gastric mucosal injury. Pioglitazone Hydrochloride is an activator of PPAR γ.
Pioglitazone is a prescription drug of the thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes have not yielded statistically significant results.
Its cardiovascular safety profile compares favorably with that of rosiglitazone, which was withdrawn from some markets after concerns about an increased risk of cardiac events. Pioglitazone has been found to be associated with bladder tumors and has been withdrawn in some countries.
Pioglitazone is used to lower blood glucose levels in the treatment of diabetes mellitus type 2 (T2DM) either alone or in combination with a sulfonylurea, metformin, or insulin.The main study that looked at the medication, however, found no statistically significant difference in the main cardiovascular outcomes that were looked at.
The secondary outcome of death from all causes, myocardial infarction, and stroke were lower. Pioglitazone has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.
How should I use this medication?
The usual starting dose for adults is 15 mg or 30 mg taken once daily, with or without food, at the same time each day. Diet and exercise programs should be continued while taking pioglitazone. Your doctor may decide to increase the dose of pioglitazone to 45 mg daily if lower doses do not sufficiently reduce your blood sugar levels. The use and dose of pioglitazone for children must be determined by their doctor.
Pioglitazone may be taken with or without food, and should be taken daily and at regular intervals as prescribed by the doctor so that blood levels of the medication always remain in an effective range.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without talking to your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible so that levels will be kept as constant as possible in the blood. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
What form(s) does this medication come in?
Each white, round tablets with imprint "PGT" one side and "15" on the other side, contains 15 mg pioglitazone HC1. Nonmedicinal ingredients: Lactose monohydrate, hydroxypropyl cellulose, carboxymethylcellulose calcium, magnesium stearate.
Each white, round tablet with imprint "PGT" on one side and "30" on the other side, contains 30 mg of pioglitazone HC1. Nonmedicinal ingredients: Lactose monohydrate, hydroxypropyl cellulose, carboxymethylcellulose calcium, and magnesium stearate.
Each white, round tablet with imprint "PGT" on one side and "45" on the other side, contains 45 mg of pioglitazone HC1. Nonmedicinal ingredients: Lactose monohydrate, hydroxypropyl cellulose, carboxymethylcellulose calcium, and magnesium stearate.
HOW TO STORE
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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